Abstract: Interrupted sampling repeater jamming (ISRJ) is an active jamming for effectively deceiving coherent radar, especially for linear frequency modulated radar, whose received signal can generate a series of false targets after pulse compression. In order to counter this kind of jamming, meanwhile, considering the high Doppler tolerance requirement of waveform in the moving target scene, a waveform design algorithm based on ambiguity function is proposed in this paper. With the cognition of jamming in advance,an optimization model is established to idealized the correlation function of the waveform to design, and the constant modulus constraint for transmitted waveform is considered. Since the problem is non-convex, an alternate cycle algorithm is proposed to solve the problem. Eventually, the effectiveness of the proposed method is verified by simulation, and the waveform designed with high Doppler tolerance can effectively suppress the ISRJ. The method proposed is robust to the cognitive bias error of the jamming.