Abstract: A new anti-interference method based on a bistatic radar system is proposed, and mainlobe interference and sidelobe interference are simultaneously suppressed through cooperation of the two radars. In this method, the interference direction information of a single radar is extracted from the radar scene using the sparse recovery technique. According to the azimuthal information of interference,the two dimensional blocking matrix method is used to block mainlobe interference, and adaptive processing technology is adopted to suppress sidelobe interference. Finally, aiming at the problem that multiple mainlobe interferences can not be cancelled in full time domain, multiple mainlobe interferences are released one by one and cancelled separately, so as to achieve the suppression of all mainlobe interferences and improve the ability of full time domain target detection. Simulation results show that the proposed method can suppress two sidelobe interferences and two mainlobe interferences at the same time, and the signal-to-noise ratio loss of the target is about 3 dB. The method can effectively suppress multiple mainlobe and sidelobe interference simultaneously, and improve the ability of target detection, especially the target in the same direction with the mainlobe interference.